Publications by authors named "J Yarney"

Article Synopsis
  • An 8-year-old girl was diagnosed with a type of cancer called alveolar rhabdomyosarcoma, located in a part of her face.
  • Doctors used a special scan to find a big tumor that affected some of her facial muscles.
  • After several treatments, including chemotherapy and radiation, she's doing great 10 years later with no signs of the cancer coming back!
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Background: The major burden of cervical cancer occurs in low- and middle-income countries. In Ghana, it is the second most common cancer among women. Infection with high-risk human papilloma virus (HPV) has been established as the cause of cervical cancer.

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Article Synopsis
  • The stromal microenvironment (SME) in breast cancer plays a crucial role in tumor behavior and response to treatment; its relationship with pre-diagnostic factors, especially in women of African ancestry, is not well understood.
  • A study analyzed 792 breast cancer patients to identify how pre-diagnostic host factors influenced SME characteristics using machine learning on tissue images, revealing that certain factors like parity and family history correlated with higher stromal cellular density.
  • The results suggest that epidemiological risk factors may impact tumor biology through changes in the SME, emphasizing the importance of considering these factors in breast cancer studies.
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Purpose: To build capacity for improved treatment of locally advanced cervical cancer in Ghana, including computed tomography (CT) staging and intensity modulated radiotherapy (IMRT).

Materials And Methods: Patients with histologically confirmed cervical cancer were prospectively staged with abdominopelvic CT and ultrasound and offered the opportunity to have IMRT instead of conventional two-dimensional radiotherapy. The development of an efficient, high-quality, and safe IMRT program was facilitated by investment in new technology and comprehensive training of the interdisciplinary radiotherapy team in collaboration with a North American center of excellence.

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Epidemiologic data on insecticide exposures and breast cancer risk are inconclusive and mostly from high-income countries. Using data from 1071 invasive pathologically confirmed breast cancer cases and 2096 controls from the Ghana Breast Health Study conducted from 2013 to 2015, we investigated associations with mosquito control products to reduce the spread of mosquito-borne diseases, such as malaria. These mosquito control products were insecticide-treated nets, mosquito coils, repellent room sprays, and skin creams for personal protection against mosquitos.

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