Publications by authors named "J Y Vis"
Background And Hypothesis: Triple-negative breast cancer (TNBC) patients are at increased risk for recurrence compared to other subtypes of breast cancer. Previous evidence showed that adiposity may contribute to worsened cancer control. Current measures of obesity, such as body-mass index (BMI), are poor surrogates of adiposity, while visceral-to-subcutaneous adiposity ratio (VSR), which can be measured from routine computed tomography (CT) imaging, is a direct adiposity measure.
View Article and Find Full Text PDFBackground: Interstitial lung disease (ILD) is rarer in children (chILD) than adults, but with increasing diagnostic awareness, more cases are being discovered. chILD prognosis is often poor, but increasing numbers are now surviving into adulthood.
Aim: To characterize chILD-survivors and identify their impact on adult-ILD centers.
Article Synopsis
- Idiopathic pulmonary fibrosis (IPF) is a severe lung disease linked to decreased physical ability and oxygen levels, both of which can predict survival rates in patients, especially when treated with antifibrotic drugs.
- This study analyzed data from patients who underwent a 6-minute walk test (6MWT) between 2015 and 2020 to evaluate how well certain test outcomes correlated with survival over two years.
- Results indicate that specific metrics from the 6MWT, particularly the minimal oxygen saturation during exercise (SpO-nadir), effectively predict mortality risk; incorporating SpO-nadir into existing survival models enhances their accuracy for clinical use in IPF care.
Background: Patients with stable chest pain suspected of coronary artery disease (CAD) usually undergo multiple diagnostic tests to confirm or rule out obstructive CAD. Some tests may not effectively assess the presence of CAD, precluding optimal treatment. A diagnostic strategy of upfront computed tomography coronary angiography (CTCA) combined with optimal medical therapy (OMT) tailored to the extent of CAD may be superior to standard care in preventing major adverse cardiac events.
View Article and Find Full Text PDFBackground: It is difficult to recognize vitamin B12 deficiency and to evaluate the effect of B12 treatment due to a broad range of variable clinical symptoms overlapping with other diseases and diagnostic biomarkers that quickly normalize during treatment. This poses a risk of delay in diagnosis and a challenge to uniformly monitor the effect of B12 treatment. There is a need for a new clinical outcome measure suitable for clinical practice and clinical evaluation studies.
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