Publications by authors named "J Y Nasr"
Objective: The aim of the study is to assess the diagnostic accuracy of 4-dimensional computed tomography (4D-CT) scans for patients with primary hyperparathyroidism (pHPT) after negative or inconclusive Technetium-99m sestamibi single-photon emission computed tomography scan.
Methods: A literature search of several databases was conducted from inception to August 2023. Eligible studies reported adult patients (>18 years old) who underwent 4D-CT after negative or inconclusive sestamibi results.
Profiteering optical biosensors for swift assaying clanobutin residues in food samples, baby food and surface water: Comparative greenness, whiteness and blueness assessment.
Spectrochim Acta A Mol Biomol Spectrosc
November 2024
In livestock systems, clanobutin sodium (CLB) is a pivotal veterinary medication due to its appetite-stimulant features. This contribution aims to design, for the first time, a straightforward and ecological framework for quantifying CLB in various matrices. Relying on a direct mix-and-read assay, tyrosine (TS) and tryptophan (TP) biosensors were exploited as turn-off fluorescence probes for quantifying CLB using λ 274/302 nm and 272/361 nm, respectively.
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- * The research reviewed 18 studies involving 803 patients and found in-hospital mortality and major bleeding rates were low, at 1.8% and 2.1% respectively.
- * Results showed significant improvements in oxygen saturation and blood pressure after the procedure, suggesting that CDT offers beneficial hemodynamic outcomes and a favorable safety profile, supporting its increased use in clinical settings.
Boosting bepotastine fluorescence by switching off intramolecular photoinduced electron transfer: Application to eye drops and aqueous humor.
Spectrochim Acta A Mol Biomol Spectrosc
February 2025
Bepotastine (BPT), a second-generation antihistamine used for treating allergic rhinitis and pruritus, requires precise dosage calculation and accurate measurement in aqueous humor to ensure therapeutic efficacy and avoid adverse effects. This study presents a highly sensitive, cost-effective, readily-implementable, and ecologically sustainable method to detect BPT by enhancing its weak native fluorescence. This has been achieved by switching off the intramolecular photoinduced electron transfer (PET) process through phosphoric acid-induced protonation of the nitrogen in the piperidinyl ring.
View Article and Find Full Text PDFThe epidemiology of gram-negative bacteremia in Lebanon: a study in four hospitals.
Ann Clin Microbiol Antimicrob
October 2024
Article Synopsis
- Gram-negative bacteremia is a severe infection that is becoming more common and harder to treat due to antibiotic resistance, particularly in Lebanon where data is scarce.* -
- A study of 2400 patients revealed that infections were mainly caused by bacteria like E. coli and Klebsiella pneumoniae, with increasing resistance to critical antibiotics like carbapenems.* -
- The findings highlight the urgent need for better monitoring and data collection to improve treatment strategies for gram-negative bacteremia in Lebanon, as certain resistant strains are linked to higher mortality rates.*