On the origin of mitosis-derived human embryo aneuploidy.

Chromosome segregation errors are common in the early stages of human embryonic development. By examining the first mitotic divisions of human embryos using live cell imaging, three recent studies identify spindle architecture and positioning features that could provide insights into why early embryos are predisposed to chromosomal abnormalities.

Efficacy and safety of ephedra-containing oral medications: a systematic review, meta-analysis, and exploratory dose-response analysis for weight reduction.

Introduction: Despite the widespread use of ephedra in various forms, including food supplements and herbal prescriptions, comprehensive studies reviewing its efficacy and safety across different countries are lacking.

Methods: We systematically searched 5 electronic databases and conducted a meta-analysis of 16 randomized controlled trials (RCTs) on ephedra-containing oral medications (EOMs), performing a dose-response analysis for weight loss.

Results: The meta-analysis results revealed a statistically significant reduction in the body mass index (BMI) (MD: 1.

Risk Assessment of Selected CCS Wells through Feature, Event, and Process Method and Comparison of the Barrier Effect.

To reduce the CO release in the atmosphere, the carbon capture and sequestration (CCS) technique presents a solution in which the CO is captured from the emitting source and injected into a suitable geological formation in the subsurface. For the CCS project to be successful, CO must be trapped underground for hundreds of years. In that respect, good integrity plays an important role as it ensures that the injected CO remains sequestrated in the subsurface.