Clinical Best Practices for Radiation Safety During an Alpha DaRT Treatment.

Alpha DaRT is a new alpha radiation treatment for treating solid tumors and is currently being evaluated through clinical trials worldwide. Being a novel radiation treatment, it is important to discuss the safety considerations and procedures that are needed to ensure safe use of this unique approach. The objective of this article is to provide a set of recommendations-radiation safety best practices that were developed based on operational and clinical experience.

A dynamical calo-porosimeter to characterize wetting and drying processes in lyophobic nanometric pores.

Lyophobic heterogeneous systems, based on porous fluids made of ordered nanoporous particles immersed in a non-wetting liquid, constitute systems of interest for exploring wetting, drying, and coupled transport phenomena in nanometric confinement. To date, most experimental studies on the forced filling and spontaneous emptying of lyophobic nanometric pores, at pressures of several tens of MPa, have been conducted in a quasi-static regime. However, some studies have shown that dynamical measurements are essential to shed light on the rich physics of these phenomena.

Clinical and economic impact of pharmacist interventions to identify drug-related problems in multidisciplinary cancer care: a prospective trial.

Background: The prescription of antitumor drugs has often been associated with drug-related problems. Pretherapeutic multidisciplinary risk assessment programs including pharmaceutical care have been established to secure the initiation of injectable and oral antitumor therapies. This prospective cross-sectional double-center study evaluated the clinical and economic impact of the pharmacist in detecting drug-related problems in patients initiating antitumor therapies.

Efficacy and safety of targeted therapies in VEXAS syndrome: retrospective study from the FRENVEX.

Objectives: Vacuoles, E1 enzyme, X-linked, autoinflammatory and somatic (VEXAS) syndrome is an adult-onset autoinflammatory disease associated with somatic ubiquitin-like modifier-activating enzyme 1 (UBA1) mutations. We aimed to evaluate the efficacy and safety of targeted therapies.

Methods: Multicentre retrospective study including patients with genetically proven VEXAS syndrome who had received at least one targeted therapy.

[Professional practices of dentists and unscheduled dental care in Nouvelle-Aquitaine (France)].

In a context of saturation of private dental practices and medical demography issues, responses to requests for emergency dental care are a poorly documented problem. In partnership with the Observatoire Regional de la Santé, the URPS Chirurgiens-Dentistes Nouvelle-Aquitaine, a union, conducted a survey of private dentists in May and June 2022. The objective was to estimate the volume of requests for unscheduled dental care and to describe the responses provided by professionals.