Observation of the clinical characteristics of chronic diarrhoea in children and evaluation of the prognostic value of nutritional and immune indicators.

Background: This research aimed to assess the clinical characteristics of chronic diarrhoea in children and explore the prognostic value of nutritional status and immune indicators.

Methods: A total of 190 patients with chronic diarrhoea from January 2017 to June 2020 were enrolled to analyze their epidemiology. The patients were divided into a better prognosis group (cured and improved) and a poor prognosis group (uncured).

Generation of tunable high-order vortex beams from a Hermite-Gaussian thin-disk laser.

We demonstrate the generation of high-order, high-power vortex modes from a Hermite-Gaussian (HG) Yb:YAG thin-disk oscillator, with tunable mode orders ranging continuously from one to ten. To the best of our knowledge, this is the highest order of HG and vortex modes obtained using a thin-disk module. The output power for most of these modes reaches up to 10 W, setting a new benchmark for intracavity high-order HG mode generation.

Focused polarization hologram with arbitrary polarization to a specified polarization conversion.

Polarization devices play a key role in many optical technologies and applications. However, traditional polarization devices are often large and lack integration, and achieving polarization conversion typically requires combining multiple devices, which makes it challenging to realize integrated optical systems. Following the current trend of optical devices, we propose a method using polarization holographic exposure to prepare polarization conversion devices.

Actl6a regulates autophagy via Sox2-dependent Atg5 and Atg7 expression to inhibit apoptosis in spinal cord injury.

Introduction: Spinal cord injury (SCI) is a severe central nervous system disorder with limited treatment options. While autophagy plays a protective role in neural repair, its regulatory mechanisms in SCI remain unclear. Actin-like protein 6A (Actl6a) influences cell fate and neural development, yet its specific role in SCI repair is not well understood.