Extraction, Isolation and Purification of Catechins and their Applications.

Catechins, the main active components of tea polyphenols, boast remarkable antioxidant activities because of their unique structures. This translates to a range of potential health benefits, including fighting antibacterial, inflammation, and even cancers. However, extracting these beneficial compounds can be tricky as they're prone to degradation.

Targeting Synthesis of Diatomic Catalysts by Selective Etching and Sequential Adsorption of Metal Atom.

Diatomic catalysts featuring a tunable structure and synergetic effects hold great promise for various reactions. However, their precise construction with specific configurations and diverse metal combinations is still challenging. Here, a selective etching and metal ion adsorption strategy is proposed to accurately assign a second metal atom (M) geminal to the single atom site (M-N) for constructing diatomic sites (e.

Synthesis and antitumor activity of ultra-low molecular weight hyaluronic acid-decorated camptothecin conjugates.

Camptothecin (CPT) exhibits potent anticancer activity, but its clinical application is limited by poor solubility and severe side effects. Hyaluronic acid (HA) is gaining attention in drug delivery systems due to its excellent biocompatibility and tumor-targeting properties. In this study, we conjugated CPT to the reducing end of ultra-low molecular weight HA to create a series of HA-decorated CPT conjugates.

Predicting In-Hospital Mortality in Patients With End-Stage Renal Disease Receiving Extracorporeal Membrane Oxygenation Therapy.

Introduction: Patients on extracorporeal membrane oxygenation (ECMO) often experience worse renal outcomes and higher mortality rates as the severity of kidney injury increases. Nevertheless, the in-hospital mortality risks of patients with end-stage renal disease (ESRD) are poorly understood. This study evaluated several prognostic factors associated with in-hospital mortality in patients with ESRD receiving ECMO therapy.

Disentangling activity-stability trade-off in the catalytic degradation of malodorous sulfur-containing VOCs driven by active sites' self-dynamic evolution.

The catalytic degradation of malodorous sulfur-containing volatile organic compounds (S-VOCs), especially methanethiol (CHSH), faces an enormous challenge in striking a balance between activity and stability. Herein, we develop the time-tandem and spatial-extended strategy for synthesizing t-MoO/meso-SiO nano-reactor-type catalysts and reveal the migration and transformation behaviors of both carbon and sulfur species at the mesoscopic scale to break the catalytic CHSH activity and stability trade-off. The dynamic evolution of active centers from initial oxygen sites and acid sites to sulfur vacancies in MoS during the reaction process as well as the formation of a new dimethyl disulfide (CHSSCH) reaction pathway are identified as the main reason for the catalysts' superior activity and sulfur resistance.