Publications by authors named "J Wongpiyabovorn"
This study presents a comprehensive comparative proteomic analysis aimed at elucidating the molecular mechanisms underlying male androgenetic alopecia (AGA) and female AGA. Scalp samples from both male AGA and female AGA patients, along with their respective normal controls, were subjected to proteomic analysis, followed by bioinformatics investigations. Our findings revealed distinct proteomic profiles between male AGA and female AGA, with a total of 68 differentially expressed proteins identified in male AGA and 84 in female AGA.
View Article and Find Full Text PDFA large scale multicentre randomized, placebo-controlled subcutaneous house dust mite allergen immunotherapy (HDM SCIT) in allergic rhinitis: MITAR Study.
Asian Pac J Allergy Immunol
September 2024
Background: Previous house dust mite subcutaneous immunotherapy (HDM SCIT) placebo-controlled trials have small sample sizes and lack a consensus on baseline treatment.
Objective: To determine the efficacy of HDM SCIT in moderate-to-severe allergic rhinitis (AR) patients treated with an intranasal corticosteroid at baseline.
Methods: We conducted a randomized, placebo-controlled trial comparing HDM SCIT against placebo in Dermatophagoides pteronyssinus (Der p) sensitized.
Article Synopsis
- The Elecsys HCV Duo immunoassay can detect both antibodies to hepatitis C virus and HCV core antigen, showing strong diagnostic performance in blood donors.
- The study involved blood samples from 100 healthy controls and 200 HCV-infected patients, assessing the assay's ability to diagnose active HCV infection and evaluate response to treatment with direct-acting antivirals.
- Results indicated that the assay had high sensitivity and specificity for diagnosing HCV, with a 96.5% sustained virological response rate among treated patients, making it a useful tool for managing HCV in different populations, including those with HIV.
Article Synopsis
- - Psoriasis is a chronic skin condition where the growth of skin cells is more active than inflammation, particularly in the lesional center of the skin, and this growth is influenced by various growth factors (GFs).
- - The study analyzed skin samples from psoriasis patients to identify differentially expressed genes (DEGs) and found that specific growth factors (like EGF, FGF, PDGF, and HGF) are significantly involved in skin cell growth and inflammation.
- - The research suggests that these GFs may regulate gene expression related to both inflammation and growth in the affected skin areas, pointing toward potential new therapeutic targets for treating psoriasis.