Publications by authors named "J Wilkens"

Article Synopsis
  • Proton Minibeam Radiation Therapy has been promising in enhancing treatment efficacy compared to traditional radiation, but more research into its biological mechanisms is needed.
  • A mechanical collimation setup was developed to produce 250µm minibeams with a 1000µm spacing, with optimization using Monte Carlo simulations conducted at various proton therapy sites.
  • Results showed a peak-to-valley dose ratio (PVDR) of 10 in Dresden and 14 in Seattle, with some discrepancies between dosimetry methods that can be addressed with correction factors.
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Purpose: Microbeam radiation therapy (MRT) has shown superior healthy tissue sparing at equal tumour control probabilities compared to conventional radiation therapy in many preclinical studies. The limitation to preclinical research arises from a lack of suitable radiation sources for clinical application of MRT due to high demands on beam quality. To overcome these limitations, we developed and built the first prototype of a line-focus X-ray tube (LFXT).

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In the present study, we analysed fertility and longevity traits of 22 sheep breeds from Germany with a suitable quantity of data in the national database OviCap. The data comprised merino, meat, country and milk sheep breeds with 62,198 ewes and about 173,000 lambing records, until the fifth lambing. Across-breed means of heritabilities reached estimates of 0.

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Water-based polyurethane dispersions (PUDs) show a characteristic dependency of the electrophoretic mobility on the electrolyte concentration, which can be investigated by hard and soft particle models. For this purpose, additional information can be obtained by determining particle charges and electrostatic potentials. PUDs with different contents of an intrinsic ionic stabilizer and various polyol components were synthesized according to the acetone process.

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Therapists' responses to challenging therapy situations on the Facilitative Interpersonal Skills (FIS) performance task are a significant predictor of therapists' differences in treatment outcomes. The aim of this study was to assess whether the complexity of the therapy situation influenced the facilitative interpersonal skills of trainees. Trainee therapists (n=46) participated in an experiment in which they responded to a set of challenging and benign (i.

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