Mitochondrial cannabinoid receptors gate corticosterone impact on novel object recognition.

Corticosteroid-mediated stress responses require the activation of complex brain circuits involving mitochondrial activity, but the underlying cellular and molecular mechanisms are scantly known. The endocannabinoid system is implicated in stress coping, and it can directly regulate brain mitochondrial functions via type 1 cannabinoid (CB) receptors associated with mitochondrial membranes (mtCB). In this study, we show that the impairing effect of corticosterone in the novel object recognition (NOR) task in mice requires mtCB receptors and the regulation of mitochondrial calcium levels in neurons.

Gambling involvement among Native Americans, Blacks, and Whites in the United States.

Background And Objectives: This paper examines risk factors of gambling and problem gambling among racial subgroups in the U.S. population, namely Native Americans and blacks, for whom research data are lacking.

Predictors of Problem Gambling in the U.S.

In this article we examine data from a national U.S. adult survey of gambling to determine correlates of problem gambling and discuss them in light of theories of the etiology of problem gambling.

The Relationship Between Distance from Gambling Venues and Gambling Participation and Problem Gambling Among U.S. Adults.

In this article we examine the relationship between extent of gambling for U.S. adults and the distance from their residence to the nearest casino or track.