Publications by authors named "J Wells Logan"
Hepatitis B elimination objectives can only be realised if new patient linkage to care is matched by long-term patient retention in care. We previously showed in adult chronic hepatitis B (CHB) patients that retention in care was inferior in younger patients and in patients from non-Asian ethnicities. The present study explores further the rates and determinants of loss to follow-up in a cohort of 271 young patients (aged 16-21 years at baseline).
View Article and Find Full Text PDFMetabolic reprogramming is a hallmark of cancer, crucial for malignant transformation and metastasis. Chronic lymphocytic leukaemia (CLL) and prostate cancer exhibit similar metabolic adaptations, particularly in glucose and lipid metabolism. Understanding this metabolic plasticity is crucial for identifying mechanisms contributing to metastasis.
View Article and Find Full Text PDFIntroduction: Trachoma is caused by the bacterium (). The WHO recommends the SAFE strategy for trachoma elimination: Surgery for trichiasis, Antibiotics, Facial cleanliness and Environmental improvement. Multiple rounds of SAFE implementation have proven insufficient to eliminate trachoma in Ethiopia, where over 50% of the global trachoma burden remains.
View Article and Find Full Text PDFArticle Synopsis
- Adolescent girls and young women (AGYW) aged 15-24 are at a higher risk for HIV compared to young men, highlighting the need for targeted prevention strategies.
- A Bayesian spatial model was created to analyze household health survey data from 13 sub-Saharan African countries, estimating individual risk factors and population viral load (PVL) to identify high-risk AGYW districts.
- The study found that PVL is the strongest predictor of HIV positivity, with significant increases in risk associated with having an HIV-positive partner, enabling better targeting of prevention efforts.
Article Synopsis
- Mosquito-borne viruses pose a major health threat globally, highlighting the need for effective personal protection against insect bites.
- A new repellent compound, delta-undecalactone, showed exceptional efficacy, offering nearly 100% initial protection and over 50% bite prevention for over 7 hours when applied to skin and clothing.
- Mathematical modeling suggests widespread use of this repellent could significantly reduce Zika virus infections during outbreaks, demonstrating its potential as a cost-effective strategy to combat arboviral diseases like dengue and chikungunya.