Publications by authors named "J Wefer"

Article Synopsis
  • Predator-prey interactions in ecosystems create complex food webs with a universal trend of larger predators compared to their prey, which helps stabilize communities.
  • The study developed predator-trait models to predict body-mass ratios from a comprehensive database of 290 food webs across various ecosystems.
  • It was found that specific predator traits, such as size and movement type, significantly influence the body-size relationships, aiding in understanding and managing ecosystem stability.
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Background: We have previously shown that vaccination with DNA encoding the encephalitogenic peptide myelin oligodendrocyte glycoprotein (MOG)(91-108) (pMOG) suppresses MOG(91-108)-induced rat Experimental Autoimmune Encephalomyelitis (EAE), a model for human Multiple Sclerosis (MS). The suppressive effect of pMOG is dependent on inclusion of CpG DNA in the plasmid backbone and is associated with early induction of Interferon (IFN)-beta.

Principal Findings: In this study we examined the mechanisms underlying pMOG-induced protection.

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The objective of this study was to investigate the limitations of a heterologous bladder acellular matrix graft (BAMG) and the influence of the collagen ratio on functional regeneration in a large animal model. Ten female dogs underwent partial cystectomy; eight received BAMG (two homologous; six heterologous) and two partial cystectomy only. A cystometry was performed prior to surgery and 7 months postoperatively when all animals underwent sacral root stimulation.

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