Publications by authors named "J Waninger"
Article Synopsis
- Conjunctival melanoma (CJM) is a rare form of mucosal melanoma, and understanding its genetics is improving, but predicting patient outcomes remains difficult; this study investigates whether a 31-gene expression profile test (originally for skin melanoma) can help in prognosis for CJM patients.* -
- The study involved a review of 10 CJM patients, using archived tumor samples to perform gene expression testing, with follow-up for patient outcomes such as recurrence and metastasis over a minimum of 5 years.* -
- Results showed that 50% of patients developed metastatic disease, significantly impacting survival rates, and highlighted that reduced expression of the gene BAP1 may play a crucial role in determining metastatic risk
Purpose: To describe a case of perfluoro-n-octane (PFO) retention, migration into the anterior chamber, and the subsequent formation of iris nodules after the repair of a giant retinal tear.
Methods: Patient data were collected by a manual chart review. All patient information was deidentified.
The liver is a common site of metastasis for many primary malignancies, but the quantitative impact on survival is unknown. We performed a systematic review and meta-analysis of 83 studies (604,853 patients) assessing the overall hazard associated with liver metastases by primary tumor type and treatment regimen. The pooled overall survival hazard ratio (HR) for all included studies was 1.
View Article and Find Full Text PDFNeoadjuvant Immune Checkpoint Inhibition in Metastatic Conjunctival Melanoma.
Ophthalmic Plast Reconstr Surg
November 2023
The development of immune checkpoint inhibitors (ICI) has transformed the treatment of advanced-stage cutaneous melanoma; however, most trials did not include patients with conjunctival melanoma. Herein the authors describe a patient with recurrent conjunctival melanoma who developed locally advanced, b-raf and v-raf murine sarcoma viral oncogene homolog B1-negative melanoma in her nasal cavity and extensive, metabolically active, bilateral lymphadenopathy in her thorax. Her nasal mass measured 4.
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