Publications by authors named "J Wambugu"
Article Synopsis
- Understanding SARS-CoV-2 infection in vulnerable populations, like those in Kakuma Refugee Camp in Kenya, is essential for controlling the disease.
- From March 2020 to December 2021, data showed that out of 18,864 tests, there were 1,024 positive cases among refugees and the host community, with calculated attack rates and case fatality ratios (CFR) for both groups.
- While refugees had a lower attack rate of 325.0/100,000 but a higher CFR of 2.9% compared to the host community, this highlights the urgent need for targeted COVID-19 prevention strategies, especially vaccination efforts.
Implementing new diagnostics in public health programs can involve difficult trade-off decisions between individual patient benefits and public health considerations. Such decision-making processes are often not documented and may not include engagement of affected communities. This paper examines the perspectives of stakeholders on the trade-off between over-treatment and missed diagnosis captured during decision-making workshops on the transition from use of Xpert MTB/RIF to diagnose tuberculosis to Xpert MTB/RIF Ultra in Kenya and Swaziland.
View Article and Find Full Text PDFBackground: We aimed to determine the prevalence of pulmonary TB amongst the adult population (≥15 years) in 2016 in Kenya.
Method: A nationwide cross-sectional survey where participants first underwent TB symptom screening and chest x-ray. Subsequently, participants who reported cough >2weeks and/or had a chest x-ray suggestive of TB, submitted sputum specimen for laboratory examination by smear microscopy, culture and Xpert MTB/RIF.
Setting: All 19 public health laboratories in Swaziland that had Xpert(®) MTB/RIF machines installed as part of a countrywide roll-out between June 2011 and June 2014.
Objective: To evaluate the utilisation and functionality of Xpert from 2011 to mid-2014.
Design: Descriptive study of Xpert implementation using routinely collected data.
African bovine trypanosomiasis caused by Trypanosoma sp., is a major constraint on cattle productivity in sub-Saharan Africa. Some African Bos taurus breeds are highly tolerant of infection, but the potentially more productive Bos indicus zebu breeds are much more susceptible.
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