Publications by authors named "J Walusiak-Skorupa"
Background: Exposure-related changes in exhaled nitric oxide (FeNO) and sputum eosinophils have not been thoroughly compared in the investigation of occupational asthma.
Objective: This study aimed at comparing the accuracies of the changes in FeNO concentrations and sputum eosinophil counts in identifying asthmatic reactions induced by occupational agents during specific inhalation challenges (SICs).
Methods: This retrospective multicenter study included 321 subjects who completed an assessment of FeNO and sputum eosinophils before and 24 h after SICs with various occupational agents, of whom 156 showed a positive result.
Human well-being is affected by demographic, geographical, environmental and economic changes in the modern world. Advanced and rapid technological advances have left countries without an adequate structural framework. The One Health concept, rooted in the interconnectedness of human health, animal health and the environment, addresses today's global health challenges.
View Article and Find Full Text PDFThe set up of new healthcare models by taking into account diagnosis and health education of the viral infection, aims to achieve the goals of the World Health Organization Global Health Sector Strategy on viral diseases for 2022-2030. In comparison to Europe, Poland is ranked among countries with an moderate prevalence of hepatitis B and C virus (HBV and HCV), also human immunodeficiency virus (HIV). An additional challenge is the changing epidemiological situation due to the impact of immigrants, resulting mainly from the war in Ukraine.
View Article and Find Full Text PDFThe impact of exposure to tobacco smoke and e-cigarettes on asthma-related outcomes: Systematic review informing the EAACI guidelines on environmental science for allergic diseases and asthma.
Allergy
September 2024
Article Synopsis
- - The European Academy of Allergy and Clinical Immunology analyzed systematic reviews using GRADE to assess the effects of environmental tobacco smoke (ETS) and active smoking on asthma-related issues, focusing primarily on longitudinal studies.
- - Prenatal and postnatal ETS are linked to an increased risk of recurrent wheezing and new-onset asthma, with moderate to low certainty evidence indicating that combined ETS exposure heightens these risks.
- - Active smoking is associated with severe asthma exacerbations and poor asthma control, also backed by moderate certainty evidence, alongside potential impacts on quality of life and lung function.
Article Synopsis
- The study evaluated the effectiveness of specific IgE (sIgE) testing for wheat and rye flour in diagnosing occupational asthma compared to a specific inhalation challenge (SIC), which is considered the gold standard.
- Results showed that sIgE levels of 0.35 kU/L or greater had similar diagnostic sensitivity and specificity to the SIC, but higher sIgE thresholds increased specificity significantly.
- The findings suggest that high sIgE levels can effectively indicate flour-induced occupational asthma, while low levels in patients with a positive SIC may correlate with lower T2 inflammatory biomarkers.