Publications by authors named "J Walk"
Article Synopsis
- High levels of a specific protein related to vitamin K deficiency were linked to worse outcomes in COVID-19 patients, indicating the potential importance of vitamin K in managing the disease.
- A clinical trial was conducted with 40 hospitalized patients, where half received vitamin K2 supplements and the other half received a placebo, focusing on their impacts on vitamin K status and related health markers.
- Results showed that vitamin K2 supplementation was safe and significantly improved vitamin K status but did not demonstrate a protective effect against the breakdown of elastic fibers in the body.
Soils in hyper-arid climates, such as the Chilean Atacama Desert, show indications of past and present forms of life despite extreme water limitations. We hypothesize that fog plays a key role in sustaining life. In particular, we assume that fog water is incorporated into soil nutrient cycles, with the inland limit of fog penetration corresponding to the threshold for biological cycling of soil phosphorus (P).
View Article and Find Full Text PDFBackground: Here we assessed a possible relationship between baseline TGF-β concentrations and acquisition of sterile immunity after Plasmodium falciparum sporozoite immunization.
Methods: TGF-β concentrations were determined in samples of 65 malaria-naive volunteers in 4 studies either prior to and after challenge infection, or prior to and after first immunizing infection under chemoprophylaxis with P. falciparum sporozoites.
Background: Whole sporozoite immunization under chemoprophylaxis (CPS regime) induces long-lasting sterile homologous protection in the controlled human malaria infection model using Plasmodium falciparum strain NF54. The relative proficiency of liver-stage parasite development may be an important factor determining immunization efficacy. Previous studies show that Plasmodium falciparum strain NF135 produces relatively high numbers of large liver-stage schizonts in vitro.
View Article and Find Full Text PDFObjectives: Vitamin K deficiency consistently associates with worse clinical outcome in COVID-19 patients. However, whether this is due to increased expenditure during inflammation or poor vitamin K status prior to infection remained unknown.
Methods: Dp-ucMGP levels of 128 individuals were measured for the post-MONICA study and were compared to SARS-CoV-2 PCR testing results.