The effects of nitrous oxide on anxious young pediatric patients across sequential visits: a double-blind study.

Nitrous oxide has acquired widespread use as a tool for managing young dentally anxious children. Clinical impressions have suggested it eliminates uncooperative behavior while alleviating anxiety and facilitating coping skills. Data to support these claims documenting the effects of nitrous oxide across sequential visits has not previously been presented.

Development of home orientation in offspring of protein-restricted cats.

The development of home orientation was evaluated in 2-14-day-old kittens nursing from mothers fed a protein-restricted or control diet during late gestation and lactation. Although restricted kittens remained in the home when placed in it, their ability to return to the home was delayed when they were removed from it. Restricted kittens also exhibited aberrant locomotor development and an increased frequency of loss of balance (upsets) en route to the home.

Behavioral correlates of focal hippocampal x-irradiation in rats II. Behavior related to adaptive function in a natural setting.

Prior investigations have shown the effects of hippocampal degranulation on behaviors such as two-way avoidance, open-field behavior, and operant schedules of reinforcement. Little, however, has been done with behaviors related to adaptive function in a natural setting; the present study has addressed this issue. Long-Evans hooded rats, subjected to focal neonatal X-irradiation of the hippocampus, were tested in passive avoidance and four dominance situations.

The effects of preparturient avoidance conditioning on postnatal caretaker behavior and offspring catecholamine levels and behavior in C57BL/6J mice.

Avoidance conditioning during pregnancy, changes in caretaker behavior during lactation, and changes in offspring catecholamine levels and behavior were investigated in C57BL/6J mice. Three equal groups of mice were employed. One group was avoidance conditioned prior to pregnancy and continued to avoid shock during pregnancy; a 2nd group was avoidance conditioned during pregnancy; and the 3rd group served as untreated controls.