Publications by authors named "J W Westley"

Microbes are key drivers of global biogeochemical cycles, and their functional roles arey dependent on temperature. Large population sizes and rapid turnover rates mean that the predominant response of microbes to environmental warming is likely to be evolutionary, yet our understanding of evolutionary responses to temperature change in microbial systems is rudimentary. Natural microbial communities are diverse assemblages of interacting taxa.

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Background: As shift workers, nurses are at an increased risk of drowsy driving because of long hours at work and/or short sleep periods between shifts.

Methods: In this study, a descriptive cross-sectional cohort design was used to examine the prevalence of drowsy driving among nurses.

Findings: An electronic survey was sent to 7,217 nurses of which 2,205 (30.

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A protein binding-induced supramolecular dissociation strategy is developed with the ratio of monomer and excimer fluorescence as the tool for protein sensing and quantification. Due to the "lock-and-key" strategy based on specific ligand-protein binding, the probe exhibits excellent selectivity and quantification accuracy to the protein of interest. The ratiometric approach is immune to interference from extrinsic quenchers, while preserving the opportunity to be protein specific.

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Understanding the molecular rules behind the dynamics of supramolecular assemblies is fundamentally important for the rational design of responsive assemblies with tunable properties. Herein, we report that the dynamics of temperature-sensitive supramolecular assemblies is not only affected by the dehydration of oligoethylene glycol (OEG) motifs, but also by the thermally-promoted molecular motions. These counteracting features set up a dynamics transition point (DTP) that can be modulated with subtle variations in a small hydrophobic patch on the hydrophilic face of the amphiphilic assembly.

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Long working hours have been shown to negatively impact adverse events in health care. In this study, a retrospective correlational design was used to evaluate the relationship between working hours and near-miss medication error alerts. During a two-year period, 5372 nurses triggered 420,706 near-miss alerts on 9, 285, 786 medication administrations.

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