Publications by authors named "J W Vlieger"

Public-Private Partnerships (PPPs) have been crucial in medicine research and development (R&D) for decades. Initially, PPPs involved private and academic innovators working in bilateral collaborations to advance pharmaceutical innovation. Later, a precompetitive open innovation environment was created, where multiple public and private innovators collaborated on mutual interests.

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The European Lead Factory (ELF) is a consortium of universities and small and medium-sized enterprises (SMEs) dedicated to drug discovery, and the pharmaceutical industry. This unprecedented consortium provides high-throughput screening, triage, and hit validation, including to non-consortium members. The ELF library was created through a novel compound-sharing model between nine pharmaceutical companies and expanded through library synthesis by chemistry-specialized SMEs.

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Article Synopsis
  • - The study investigates how COVID-19 lockdowns in the Netherlands impacted myopia (nearsightedness) in teenagers, particularly regarding their nearwork activities and outdoor time.
  • - Findings reveal that nearwork increased significantly during the lockdown, with time spent on non-educational activities rising by nearly 50%, while outdoor time remained relatively unchanged.
  • - The increase in nearwork persisted even after lockdowns ended, suggesting a potential rise in myopia prevalence and progression among European children following the pandemic.
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Background: The 15-item Quality of Recovery-15 (QoR-15) scale is strongly recommended as a standard patient-reported outcome measure assessing the quality of recovery after surgery and anesthesia in the postoperative period. This study aimed to validate the Dutch translation of the questionnaire (QoR-15NL).

Materials And Methods: An observational, prospective, single-centre cohort study was conducted.

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