Impact of Dataset Size on 3D CNN Performance in Intracranial Hemorrhage Classification.

This study aimed to evaluate the effect of sample size on the development of a three-dimensional convolutional neural network (3DCNN) model for predicting the binary classification of three types of intracranial hemorrhage (ICH): intraparenchymal, subarachnoid, and subdural (IPH, SAH, SDH, respectively). During the training, we compiled all images of each brain computed tomography scan into a single 3D image, which was then fed into the model to classify the presence of ICH. We divided the non-hemorrhage quantities into 20, 30, 40, 50, 100, and 150 and the ICH quantities into 20, 30, 40, and 50.

Real-World Characterization of Toxicities and Medication Management in Recipients of CAR T-Cell Therapy for Relapsed or Refractory Large B-Cell Lymphoma in Nova Scotia, Canada.

Nova Scotia (NS) began offering CAR T-cell therapy as a third-line standard of care for eligible patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) in 2022. Recipients of CAR T-cell therapy often experience acute toxicities, including cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS), which require close monitoring and prompt management. This retrospective review aimed to describe the characteristics of adult patients with r/r LBCL deemed eligible to receive CAR T-cell therapy with axicabtagene ciloleucel in NS between January 2022 and June 2024, the toxicities experienced and toxicity management, hospital visits and intensive care unit (ICU) admissions, the utilization of toxicity management guidelines, and general efficacy outcomes.

Care professionals' experiences and mediation of conditions for well-functioning interprofessional collaboration: a mixed-methods case study of rehabilitation pathways in Danish home care.

There is a growing interest in understanding the conditions that facilitate and hinder well-functioning interprofessional collaborations in healthcare. However, important knowledge gaps persist regarding the significance of context conditions and how different professional groups contribute to mediating conditions. To address these gaps, we conducted a mixed-method single-case study using surveys, interviews, and observations.

Developing evidence for a national strategy for older adults in the criminal justice system: overview of the nominal group approach for this series of brief reports.

The number of people aged 50 and over entering the criminal justice system (CJS) in England and Wales is growing. This raises questions as to the suitability of the CJS to equitably accommodate individuals with complex illness or impairment, who might experience difficulties in cognitive function, frailty, and/or impaired mobility. Findings from the government, the third sector, and academic literature have highlighted the difficulties experienced by older adults in the CJS and those tasked with supporting them.

Older women in the criminal justice system: a brief report from a nominal group.

There are increasing numbers of older women in prison in England and Wales. The needs of older women in prison have been under researched and are often unmet. This paper explores staff and expert perspectives on the needs of older women in prison through a nominal group attended by six participants, including a consultant at the UK Health Security Agency; a General Practitioner; a postgraduate student completing a project on older women in prison; an academic researcher with expertise on older women in prison; a National Women's Health, Social Care, and Environment Review Group lead; and a HMMPS Diversity and Inclusion Lead.