Publications by authors named "J W McCarty"

Background: Pseudotumor cerebri (PTC) syndrome is a disorder of increased intracranial pressure, most commonly affecting overweight women of childbearing age. Malignant PTC (MPTC) is a rare presentation that involves rapidly worsening vision, often necessitating surgical intervention to prevent permanent vision loss. The goal of this study was to determine whether radiographic findings of PTC are predictive of MPTC and the final visual outcome.

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  • Within-sample variation in cotton fiber length affects yarn production and quality, prompting the textile industry to focus on improving long fibers and reducing short ones.
  • The USTER High Volume Instrument (HVI) is commonly used for assessing fiber length but has limitations for genetic studies due to its indirect measurements.
  • The Advanced Fiber Information System (AFIS) directly measures individual fibers, providing more sensitive and accurate length data, which, when combined with genome-wide association studies (GWAS), enables better identification of genetic loci associated with fiber length variations.
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Variational flooding is an enhanced sampling method for obtaining kinetic rates from molecular dynamics simulations. This method is inspired by the idea of conformational flooding that employs a boost potential acting along a chosen reaction coordinate to accelerate rare events. In this work, we show how the empirical distribution of crossing times from variational flooding simulations can be modeled with analytical Kramers' time-dependent rate (KTR) theory.

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Background: Almost all acquired severe aplastic anaemia is immune mediated and characterised by hypocellular bone marrow and ≥2 affected haematopoietic lineages. The optimal preparartive regimen for unrelated donor transplantation remains to be established. We aimed to study long-term outcomes after unrelated donor transplantation for severe aplastic anaemia with de-escalation of cyclophosphamide (Cy) dose in steps of 50 mg/kg (150, 100, 50, 0 mg/kg) in combination with total body irradiation (TBI) 2 Gy, anti-thymocyte globulin (ATG) and fludarabine.

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  • Diagnosing spinal vascular conditions is tough due to small structures, long imaging tests, and overlapping features.
  • The authors provide strategies to help radiologists identify these conditions by focusing on vascular anatomy and imaging results.
  • Three main types of abnormalities are discussed: infarcts, anomalies, and tumors, to assist in accurate diagnosis.
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