Publications by authors named "J W McAninch"
The impact of more restrictive hydrocodone rescheduling on unintentional pediatric opioid exposures.
Pharmacoepidemiol Drug Saf
June 2024
Article Synopsis
- The study aimed to evaluate the effects of rescheduling hydrocodone combination products (HCPs) from a less restrictive schedule III to a more restrictive schedule II on unintentional pediatric exposures in children aged 5 and under.
- Analysis of U.S. data showed that after the rescheduling in October 2014, there was a significant drop in pediatric emergency department visits and poison center cases related to hydrocodone, decreasing by over 50%, while oxycodone cases remained stable and codeine cases slightly increased.
- The results suggest that the rescheduling contributed to a notable reduction in unintentional hydrocodone exposures among children, highlighting the need for continued efforts to reduce pediatric medication poisonings as a
Objective: Buprenorphine is a medication for opioid use disorder that reduces mortality. This study aims to investigate the less well-understood relationship between the dose in the early stages of treatment and the subsequent risk of death.
Methods: We used Kentucky prescription monitoring data to identify adult Kentucky residents initiating transmucosal buprenorphine medication for opioid use disorder (January 2017 to November 2019).
Introduction: Current wearables that collect heart rate and acceleration were not designed for children and/or do not allow access to raw signals, making them fundamentally unverifiable. This study describes the creation and calibration of an open-source multichannel platform (PATCH) designed to measure heart rate and acceleration in children ages 3-8 yr.
Methods: Children (N = 63; mean age, 6.
Background: The shift from prescription to illicit drugs involved in drug poisoning deaths raises questions about the current utility of prescription drug monitoring program (PDMP) data to inform drug poisoning (overdose) prevention efforts. In this study, we describe relations between specific drugs involved in Kentucky drug poisoning deaths and antecedent controlled substance (CS) dispensing.
Methods: The study used linked death certificates and PDMP data for 2,248 Kentucky resident drug poisoning deaths in 2021.
Importance: In April 2021, the US Department of Health and Human Services (HHS) released practice guidelines exempting educational requirements to obtain a Drug Addiction Treatment Act (DATA) waiver to treat up to 30 patients with opioid use disorder with buprenorphine.
Objective: To compare demographic and practice characteristics of clinicians who received traditional DATA waivers before and after release of the education-exempted HHS practice guidelines and those who were approved under the guidelines.
Design, Setting, And Participants: This survey study was conducted electronically from February 1 to March 1, 2022.