Publications by authors named "J W M M de Vocht"
Specialized multidisciplinary care improves ALS survival in Belgium: a population-based retrospective study.
Amyotroph Lateral Scler Frontotemporal Degener
May 2024
Article Synopsis
- - ALS is a neurodegenerative disease that leads to muscle weakness and has an average survival time of 2-5 years, primarily due to respiratory failure, with current treatments offering limited extensions.
- - A study at the ALS Expert Centre in Belgium examined the outcomes of 659 ALS patients, revealing that those who received multidisciplinary care had significantly longer survival compared to those who did not.
- - The survival benefits were particularly noted in patients with spinal onset ALS, while those with bulbar onset did not show a significant increase in survival, highlighting the need for specialized multidisciplinary care in managing ALS.
Prognostic value of motor and extramotor involvement in ALS.
Amyotroph Lateral Scler Frontotemporal Degener
February 2024
Objective: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder resulting in upper and lower motor neuron loss. ALS often has a focal onset of weakness, which subsequently spreads to other body regions. Survival is limited to two to five years after disease onset, often due to respiratory failure.
View Article and Find Full Text PDFAmyotrophic lateral sclerosis (ALS) is characterized by progressive loss of upper and lower motor neurons. In 10% of patients, the disorder runs in the family. Our aim was to study the impact of ALS-causing gene mutations on cerebral glucose metabolism.
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