Publications by authors named "J W Kuan"
Article Synopsis
- Understanding radiation-induced effects on the CNS is vital for assessing risks in both medical treatments (like radiotherapy) and occupations (such as nuclear workers and astronauts).
- The study uses an adverse outcome pathway (AOP) approach to connect molecular events caused by radiation to cognitive decline, identifying key events linking energy deposition to impaired learning and memory.
- Evidence for the AOP was gathered through a literature review, highlighting gaps in knowledge that need to be filled to improve risk assessments and applicability to other cognitive disorders.
A solvent-controlled regioselective rearrangement reaction of spiroindane-1,3-diones with a leaving group has been developed. In acetonitrile solvent, the spiroindane-1,3-diones were rearranged to provide tritylone alcohols, while 2-benzoylbenzoate ester derivatives were obtained if the reactions were performed in alcohols.
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- The study explored how different types of music (fast-tempo vs medium-tempo) influence recovery and psychological outcomes during high-intensity exercise in 28 participants.
- It involved multiple conditions, including exercising with and without music, to assess variables like state motivation, heart rate, and exercise enjoyment.
- Results showed only a significant increase in state motivation in the fast tempo-medium tempo condition, contradicting initial hypotheses and previous research, suggesting further investigation into music's effects on exercise is needed.
Most pharmaceutical biotechnology companies use stirred-tank bioreactors (STR) for recombinant protein manufacturing. These bioreactors are used at a variety of different scales ranging from bench to production scales, with working volumes from 10 mL to 25,000 L. Bench-scale STRs are commonly used to culture mammalian cells for process development, to troubleshoot production scale bioreactors using scale-down models (SDM), or to conduct fundamental research.
View Article and Find Full Text PDFBackground: The role of familial influence in chronic myeloid leukaemia (CML) occurrence is less defined. Previously, we conducted a study to determine the prevalence of harbouring BCR::ABL1 in our local adult normal population (designated as Study). We present our current study, which investigated the prevalence of harbouring BCR::ABL1 in the normal first-degree relatives of local CML patients (designated as Study).
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