Publications by authors named "J W Kirklin"
Analysis of diagnostic criteria for ECMO-associated pneumonia.
Infect Control Hosp Epidemiol
December 2024
Article Synopsis
- Ventilator-associated pneumonia (VAP) significantly impacts critically ill patients and contributes to high rates of illness.
- The existing criteria for diagnosing VAP do not apply to patients on extracorporeal membrane oxygenation (ECMO).
- This study analyzes the effectiveness of current VAP criteria for ECMO patients and evaluates a new proposed standard for diagnosing pneumonia in these individuals.
Early Outcomes for Management of Atrioventricular Septal Defect-Tetralogy of Fallot in the Last Decade: A Congenital Heart Surgeons' Society Study.
World J Pediatr Congenit Heart Surg
November 2024
Background: We sought to determine the management and early outcomes of complete atrioventricular septal defect-tetralogy of Fallot (AVSD-TOF) for a contemporary multicenter cohort.
Methods: Of 739 participants in the Congenital Heart Surgeons' Society AVSD cohort (January 2012-May 2021), 40 had AVSD-TOF. We first compared survival differences for patients with AVSD-TOF versus those with isolated AVSD using propensity matching.
Management of Tricuspid Atresia With Normally Related Great Arteries and Left-Sided Obstruction.
World J Pediatr Congenit Heart Surg
November 2024
Article Synopsis
- Tricuspid atresia (TA) is a heart condition affecting infants and is the second most common type of functionally univentricular heart, with rare cases of left ventricular outflow tract obstruction (LVOTO) in patients who have normally related great arteries.
- A study involving 445 patients with Type I TA showed that 3% of infants needed interventions for LVOTO, and most of those who underwent surgical procedures had promising outcomes.
- The long-term survival rate for these infants was estimated at 79% over 20 years, indicating that timely surgical management can lead to successful interventions and good heart function later in life.
The 15th Annual Report from The Society of Thoracic Surgeons Interagency Registry for Mechanically Assisted Circulatory Support includes 29,634 continuous-flow left ventricular assist devices from the 10-year period between 2014 and 2024. The outcomes reported here demonstrate continued improved survival in the current era of fully magnetically levitated devices, with a significantly higher 1-year (85.7% vs 78.
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- Arrhythmias can cause severe heart issues in children, and when they are severe, heart transplantation (HTX) may be necessary, but this group has not been distinctively studied.
- *This study aimed to look at pediatric patients who needed HTX primarily due to malignant arrhythmia (MA) and how their outcomes compared to others on the list.
- *Out of thousands listed for HTX, only 63 patients (1.4%) had MA as the reason; although they were generally older and more likely to have had cardiac arrests, their chances of surviving and recovering after transplantation were similar to those without MA.