Publications by authors named "J W Holloway"

Article Synopsis
  • - The HEALing Communities Study (HCS) aimed to reduce opioid overdose deaths in 67 affected communities by implementing health campaigns focused on opioid use disorder (OUD), overdose prevention, and stigma reduction, developed with community input.
  • - Surveys conducted via Facebook/Instagram indicated that participants in HCS communities experienced reduced stigma related to OUD and improved beliefs about the efficacy of naloxone, though recognition of campaign messages was not significantly different from control communities.
  • - The study suggests a connection between recognizing campaign messages and achieving positive outcomes, but it also raises concerns about the effectiveness of traditional evaluation methods for social media health campaigns.
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Article Synopsis
  • - Children born via cesarean delivery have a greater risk of various health issues compared to those born vaginally, but the exact reasons are still not fully understood.
  • - A meta-analysis involving over 12,000 participants found six specific DNA methylation markers in newborns linked to cesarean delivery, but these markers did not persist into childhood.
  • - The study indicates that cesarean delivery affects certain blood cell proportions at birth, but further research is necessary to understand its long-term impacts on child health.
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Hippocampal dentate gyral dysplasia is well-described in temporal lobe epilepsy and may be a risk factor for sudden, unexpected death in several populations: infants (sudden infant death syndrome [SIDS], sudden unexpected infant death [SUID]), toddlers (sudden unexpected death of a child [SUDC]), and epileptics (sudden unexpected death in epilepsy [SUDEP]). We examined reports and histopathological slides from autopsies performed at our institution from 2008 through 2016 to determine whether the presence or absence of any of the described forms of such dysplasias (duplications, hyperconvolutions, and granule cell dispersion, including bilamination), correlated with the causes of death. From well over 4000 autopsies, we identified 949 autopsies with a neuropathology examination by a neuropathologist.

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