Reversible C-C bond formation in group 4 metal complexes: nitrile extrusion β-aryl elimination.

Pyridylamides of zirconium and hafnium with [C,N,N]-ligands reversibly insert nitriles into M-C bonds leading to an observable equilibrium between the starting [C,N,N]-complexes and newly formed [N,N,N]-complexes with a ketimide moiety in a 7-membered metallacycle. The discovered reversible insertion of nitriles into M-C bonds represents an unprecedented example of β-aryl elimination from a ketimide ligand in early transition metal complexes. Experimental and computational studies suggest thermodynamic and electronic reasons for this reactivity.

Effect of maternal voice on proportion of oral feeding in preterm infants.

Objective: To determine the impact of maternal voice exposure on oral feeding in preterm infants.

Study Design: Prospective, unblinded, 2-center intervention study of infants born 28 0/7-34 6/7 weeks gestation. Infants were exposed twice daily to maternal voice for 20 min before attempting oral feeding.

Covariation of changing patent ductus arteriosus management and preterm infant outcomes in Pediatrix neonatal intensive care units.

Objective: To test the hypothesis that NICU-specific preterm infant outcomes co-vary with changes in local patent ductus arteriosus (PDA) management.

Study Design: This retrospective multicenter study examined NICU-specific aggregated data for infants born 400-1499 g (VLBW) in the Pediatrix Clinical Data Warehouse. For each NICU and each year 2006-2016 we calculated proportion of infants receiving cyclooxygenase inhibitor (COXI) and/or PDA ligation and determined NICU-specific changes in these therapies between consecutive years.

Examining the Validity of Pediatric Resident Self-Assessment in the Delivery Room.

Objective: The validity of resident self-assessment of competence in neonatal resuscitation skills has not been studied. This study was designed to test the hypothesis that residents are accurate in self-assessment of basic delivery room resuscitation and bag-and-mask ventilation (BMV) skills by comparing resident self-assessed performance with assessment by observers.

Study Design: We conducted a prospective repeated measures observational study.

Sample Size, Power, and Risk of Misclassification in Pediatric Urology Hospital Rankings.

Purpose: We investigated 2019 and 2020 U.S. News & World Report methodologies of assessing pediatric urology surgical revision rates for distal hypospadias, pyeloplasty, and ureteral reimplantation to evaluate statistical power and misclassification risks.