Publications by authors named "J W G Bentz"

Article Synopsis
  • The systematic review aimed to assess how testosterone affects uterine and ovarian health in transmasculine individuals undergoing gender-affirming surgery.
  • After analyzing 28 full-text articles, it was found that the majority of endometrial tissues were either atrophic or proliferative, with a few cases showing precancerous changes.
  • No ovarian cancers were identified, suggesting that testosterone treatment does not significantly elevate the risk of serious gynecological issues in these patients.
View Article and Find Full Text PDF
Article Synopsis
  • * The study explored connections between different types of hyperglycemia (like gestational diabetes and type 2 diabetes) and specific miRNAs in late pregnancy.
  • * Seven particular miRNAs were found to be linked to hyperglycemia and glucose levels, influencing important biological processes related to maternal and child health, such as insulin signaling and placental development.
View Article and Find Full Text PDF

Nearly all cervical cancers are caused by persistent high-risk human papillomavirus (hrHPV) infection. There are 14 recognized hrHPV genotypes (HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68), and hrHPV genotypes 16 and 18 comprise approximately 66% of all cases worldwide. An additional 15% of cervical cancers are caused by hrHPV genotypes 31, 33, 45, 52, and 58.

View Article and Find Full Text PDF

Tumors with pathogenic DICER1 mutation are rare and encompass sporadic or hereditary benign, intermediate and malignant tumors. DICER1-associated sarcomas are heterogeneous; however, the prototypical ones in the GYN-tract include embryonal rhabdomyosarcoma, adenosarcoma and moderately to poorly differentiated Sertoli-Leydig tumor. In this report, we present three unique uterine sarcomas with DICER1 mutation and remarkable diffuse round/spindle cell morphology.

View Article and Find Full Text PDF