Publications by authors named "J W Erdman"

Vitamin A deficiency (VAD) and iron deficiency anemia coexist around the world, particularly in children and women of reproductive age in low- and middle-income countries. Within this scenario, there is a known interaction between vitamin A and iron, and it has been postulated that lack of vitamin A impairs iron metabolism, leading to vitamin A deficiency anemia (VADA). Current animal, epidemiological, and clinical studies support this notion.

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  • - The study explores the link between acute hyperglycemia and intraventricular hemorrhage (IVH) following intracerebral hemorrhage (ICH), positing that IVH might lead to hyperglycemia due to a neuroendocrine stress response.
  • - Analysis of data from the ICH Deferoxamine (i-DEF) trial and an independent cohort identified hyperglycemia, history of smoking, and non-lobar ICH location as significant predictors of IVH.
  • - The findings suggest that hyperglycemia may reflect inflammatory responses to hemorrhage in the ventricles, indicating a need for further research into the underlying mechanisms.
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  • Recent research has created normative growth charts for the brain structure of rhesus macaques, filling a gap in understanding nonhuman primate neurodevelopment.
  • The study analyzed 1,522 MRI scans from 1,024 macaques to identify developmental patterns in brain volume, cortical thickness, and surface area throughout their lifespan.
  • These findings not only highlight key milestones in macaque brain development but also allow for meaningful comparisons to human brain maturation, providing a valuable resource for future neuroscience studies.
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  • The study evaluated the effects of a 12-week α-tocopherol (αT)-deficient diet on the inflammatory response of mice after an LPS injection, comparing knockout and wild-type (WT) strains.
  • αT levels in the knockout mice were significantly lower than in WT, particularly in the liver and brain, which continued to decrease after LPS treatment.
  • Grip strength decreased shortly after the LPS injection but showed partial recovery 24 hours later, indicating a transient response, while inflammatory gene expression did not differ significantly between the two mouse genotypes.
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Processed foods have been part of the American diet for decades, with key roles in providing a safe, available, affordable, and nutritious food supply. The USDA Food Guides beginning in 1916 and the US Dietary Guidelines for Americans (DGA) since 1980 have included various types of commonly consumed processed foods (e.g.

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