Effects of oral administration of levothyroxine sodium on concentrations of plasma lipids, concentration and composition of very-low-density lipoproteins, and glucose dynamics in healthy adult mares.

Objective: To evaluate glucose and lipid metabolism in healthy adult horses administered levothyroxine sodium (L-T4).

Animals: 12 healthy adult mares.

Procedure: 8 horses received an incrementally increasing dosage of L-T4 (24, 48, 72, or 96 mg of L-T4/d) for weeks 1 to 8.

Effects of oral administration of levothyroxine sodium on serum concentrations of thyroid gland hormones and responses to injections of thyrotropin-releasing hormone in healthy adult mares.

Objective: To determine the effects of levothyroxine sodium (L-T4) on serum concentrations of thyroid gland hormones and responses to injections of thyrotropin-releasing hormone (TRH) in euthyroid horses.

Animals: 12 healthy adult mares.

Procedure: 8 horses received an incrementally increasing dosage of L-T4 (24, 48, 72, or 96 mg of L-T4/d) for weeks 1 to 8.

Pharmacokinetics of xylazine, 2,6-dimethylaniline, and tolazoline in tissues from yearling cattle and milk from mature dairy cows after sedation with xylazine hydrochloride and reversal with tolazoline hydrochloride.

Xylazine hydrochloride was administered i.m. at 0.

Effectiveness of tolazoline in reversing xylazine-induced sedation in calves.

Objective: To test effectiveness of IV administration of tolazoline hydrochloride in reversing xylazine hydrochloride-induced sedation in calves.

Design: Prospective study.

Animals: 12 female and 12 male Friesian-cross calves from 5 to 7 months old.