Background: Alice in Wonderland syndrome (AIWS) is a neurological condition characterized by perceptual distortions, most of which are visual in nature (metamorphopsias). Over the past decade there has been a movement in contemporary figurative painting away from strict mimesis toward depicting distortions of the painting's subject, called disrupted realism. In certain cases the similarities between the distortions in those paintings and those characteristic of AIWS are so striking that we suspect that artists may have experienced distorted perceptions themselves and used them for creative inspiration.
View Article and Find Full Text PDFBMJ Open Gastroenterol
December 2024
Objective: Colorectal cancer (CRC) screening programmes have been implemented worldwide, but the evidence of the economic consequences of screening programmes relies on data from short-term trials. The aim of this paper was to describe the costs of CRC screening in a population-based screening programme, using administrative real-world data. Specifically, we aimed to estimate the annual costs of the screening programme and the total costs of the full programme over five consecutive screening rounds.
View Article and Find Full Text PDFBackground: Alzheimer's disease and mild cognitive impairment are often difficult to differentiate due to their progressive nature and overlapping symptoms. The lack of reliable biomarkers further complicates early diagnosis. As the global population ages, the incidence of cognitive disorders increases, making the need for accurate diagnosis critical.
View Article and Find Full Text PDFClin Transl Gastroenterol
November 2024
Introduction: 65%-70% of colorectal cancer (CRC) cases are considered sporadic; they arise under the influence of environmental factors in individuals lacking a family history of CRC. Low-risk genetic variants are believed to contribute to CRC risk, in tandem with lifestyle factors.
Methods: Six hundred sixteen nonfamilial Swedish CRC cases with at least 1 of the following 5 risk factors: smoking, excessive alcohol consumption, physical inactivity, adherence to an unhealthy diet, and excess body weight were included in this study.