Publications by authors named "J W Belcher"

Background: Chronic kidney disease (CKD) frequency is increasing in patients with cirrhosis and these individuals often experience acute kidney injury (AKI). Direct comparisons of outcomes between AKI-only vs. AKI on CKD (AoCKD) among patients with cirrhosis are not well described.

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Background: Weight and health behaviours impact on breast cancer risk. We describe trends in weight and health behaviours in women at entry to a specialist breast cancer family history clinic in Manchester, UK, and changes after clinic entry.

Methods: Questionnaires were completed at clinic entry (1987-2019, n = 10,920), and updated in 2010-11 (n = 3283).

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Introduction: Fluid assessment and management is a key aspect of good dialysis care and is affected by patient-level characteristics and potentially centre-level practices. In this secondary analysis of the BISTRO trial we wished to establish whether centre-level practices with the potential to affect fluid status were stable over the course of the trial and explore if they had any residual associations with participant's fluid status.

Methods: Two surveys (S) of fluid management practices were conducted in 32 participating centres during the trial, (S1: 2017-18 and S2: 2021-22).

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Background: Preservation of residual kidney function (RKF) in dialysis patients has been associated with improved survival. RKF in the BISTRO trial was relatively well preserved and here we describe its association with survival during the trial and extended follow-up.

Methods: RKF, measured as the average urea and creatinine clearance (GFR) or 24-hour urine volume was assessed at baseline, one, two and three months and three-monthly up to 2 years in incident haemodialysis patients.

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Article Synopsis
  • The study investigates the relationship between different causes of acute kidney injury requiring renal replacement therapy (AKI-RRT) and mortality in hospitalized patients with cirrhosis.
  • Conducted across multiple U.S. hospitals in 2019, the research included 2,063 patients, finding that 18.1% underwent AKI-RRT.
  • Results indicate that while patients with hepatorenal syndrome (HRS-AKI) received different treatment approaches compared to those with other causes of AKI, there was no significant difference in 90-day mortality risk between the two groups.
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