Publications by authors named "J W Bastian"
Purpose: The primary aim of this study is to determine the rectus abdominis tendon (RAT) insertional anatomy and consequently clarify the extension of secure mobilization of the tendon from the pubic bone in the setting of anterior approaches in pelvic and acetabular reconstruction surgery.
Materials And Methods: Eleven fresh frozen cadaveric pelvises were dissected by two fellowship-trained orthopaedic trauma surgeons utilizing the anterior intrapelvic approach (AIP). The RAT at the pubic body was dissected, and its footprint on the pubic bone was defined, marked, and measured.
Article Synopsis
- Fragility and insufficiency fractures of the pelvis and sacrum are on the rise among the elderly due to weakened bones, leading to persistent pain, reduced mobility, and a risk of loss of independence.
- While conservative treatments are an option, surgery is often preferred for unstable fractures, especially since many patients do not receive adequate preventative care for osteoporosis-related fractures.
- Diagnostic imaging is crucial for identifying these fractures, with CT scans being the gold standard, but MRI offers the highest sensitivity for detecting complex fractures, guiding treatment based on fracture type and stability.
Targeting of the estrogen receptor (ER) by anti-estrogens is the standard-of-care for patients with ER+ HER2- advanced/metastatic breast cancer. While anti-estrogens that degrade ERα (fulvestrant) or block estrogen production (aromatase inhibitors) have improved patient outcomes, clinically important challenges remain related to drug administration, limited bioavailability, lack of brain exposure, and acquired resistance due to ESR1 mutations. These limitations indicate a need for more robust ER-targeted therapies.
View Article and Find Full Text PDFBacterial endogenous endophthalmitis is caused by a breach of the blood-ocular barrier by pathogens originating from distant sites. It is a rare cause of endophthalmitis and can lead to devastating outcomes without prompt and adequate treatment. We report the case of a 50-year-old woman with a history of type II diabetes mellitus who experienced an episode of acute myocardial infarction complicated by an acute exacerbation of chronic kidney disease, catheter-related infection, bloodstream infection, bacterial endocarditis, and bilateral endogenous endophthalmitis confirmed by blood culture and bilateral vitreous culture showing growth of methicillin-sensitive (MSSA).
View Article and Find Full Text PDFPurpose: To investigate how audio-biofeedback during the instruction of partial weight-bearing affected adherence, compared to traditional methods, in older adults; and to investigate the influence of individual characteristics.
Methods: The primary outcome measure of this randomised controlled trial was the amount of load, measured as the ground reaction force, on the partial weight-bearing leg. The secondary outcome was the influence of individual characteristics on the amount of load.