Publications by authors named "J Vuopio"
Increasing trend of antimicrobial resistance among methicillin-resistant Staphylococcus aureus strains in Southwest Finland, 2007-2016: An analysis of shifting strain dynamics and emerging risk factors.
J Glob Antimicrob Resist
November 2024
Objective: Substantial rise in the annual incidence of methicillin-resistant Staphylococcus aureus (MRSA) was reported in Southwest Finland (12.4-24.9/100,000 people) between 2007 and 2016.
View Article and Find Full Text PDFPurpose: Our objective was to elucidate host dependent factors of disease severity in invasive group A Streptococcal disease (iGAS) using transcriptome profiling of iGAS cases of varying degrees of severity at different timepoints. To our knowledge there are no previous transcriptome studies in iGAS patients.
Methods: We recruited iGAS cases from June 2018 to July 2020.
Article Synopsis
- Streptococcus pyogenes, or group A Streptococcus (GAS), is the main bacterial cause of pharyngitis, yet its epidemiology is not well understood. This study focuses on GAS pharyngitis cases and emm-type distribution over two years in two Finnish Hospital Districts.
- A total of 1320 GAS pharyngitis strains were collected, with 904 from Hospital District 1 and 416 from Hospital District 2. The study found that females were more frequently affected, especially under the age of 40, and specific emm types varied by age group and season.
- The findings reveal significant differences in age distribution and types of GAS based on gender and seasonal trends, highlighting the need for further research
BackgroundInvasive infections with beta-haemolytic streptococci of Lancefield groups A (iGAS), B (iGBS) and C/G (iGCGS) are a major cause of morbidity and mortality worldwide.AimWe studied incidence trends of invasive beta-haemolytic streptococcal infections in Finland, focusing on iGCGS.MethodsWe conducted a retrospective register-based study.
View Article and Find Full Text PDFPurpose: (Group A , GAS) is an important human pathogen that can cause severe invasive (iGAS) infections. Throat carriage has been assumed to possibly lead to hematogenous seeding. Retrospective studies may estimate the incidence of throat carriage in iGAS patients inaccurately.
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