Publications by authors named "J Vosloo"

Many industries utilize deep learning methods to increase efficiency and reduce costs. One of these methods, image segmentation, is used for object detection and recognition in localization and mapping. Segmentation models are trained using labeled datasets; however, manually creating datasets for every application, including deep-level mining, is time-consuming and typically expensive.

View Article and Find Full Text PDF

Background/purpose: Depressive symptoms are prevalent in student-athletes. Evidence for the factorial validity of measures assessing depressive symptoms in student-athletes is presently absent from the literature. This study examined the best fitting factorial structure and invariance across sexes of the PHQ-9.

View Article and Find Full Text PDF

Background: Soccer requires athletes to make quick decisions in dynamic environments. Several off-court technology-based interventions have been developed to train these perceptual cognitive skills. However, the evidence for training transfer using technologies to athletic performance has been sparse.

View Article and Find Full Text PDF

Tryptocidine C (TpcC, cyclo[D-Phe-Pro-Trp-D-Trp-Asn-Gln-Trp-Val-Orn-Leu]) is a broad-spectrum antimicrobial peptide in the tyrothricin complex produced by a soil bacterium, Brevibacillus parabrevis. Electrospray mass spectrometric studies reveal the oligomerisation of TpcC into dimers and higher oligomers, analogous to tyrocidine C (TrcC, Trp replaced by Tyr). Ion mobility mass spectrometry (IMMS) further confirms the formation of stable peptide dimers and tetramers with diameters of 2.

View Article and Find Full Text PDF

The concepts of polymer-peptide conjugation and self-assembly were applied to antimicrobial peptides (AMPs) in the development of a targeted antimalaria drug delivery construct. This study describes the synthesis of α-acetal, ω-xanthate heterotelechelic poly(-vinylpyrrolidone) (PVP) via reversible addition-fragmentation chain transfer (RAFT)-mediated polymerization, followed by postpolymerization deprotection to yield α-aldehyde, ω-thiol heterotelechelic PVP. A specific targeting peptide, GSRSKGT, for -infected erythrocytes was used to sparsely decorate the α-chain ends via reductive amination while cyclic decapeptides from the tyrocidine group were conjugated to the ω-chain end via thiol-ene Michael addition.

View Article and Find Full Text PDF