Publications by authors named "J Vater"

Article Synopsis
  • Gray mold disease, caused by the fungus Botrytis cinerea, is a significant threat to fruits like strawberries and tomatoes, prompting research on using Bacillus spp. volatile organic compounds (VOCs) as eco-friendly biocontrol agents.
  • In vitro tests showed that VOCs from Bacillus sp. LNXM12 were the most effective, inhibiting fungal growth by 61.2% and demonstrating a higher control efficacy on infected fruits compared to other strains.
  • Further analysis identified 22 VOCs, with synthetic compounds ethyloctynol and 3-methyl-2-pentanone (3M2P) showing strong inhibition of fungal growth and downregulating virulence genes in B. cinerea
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Tinnitus-the perception of sound despite the absence of an external source-can be a debilitating condition for which there are currently no pharmacological remedies. Our proof of concept study focused on the immediate effects of non-invasive electrical stimulation through the ear canal on loudness and tinnitus-induced distress. In addition, we aimed to identify variables that may affect the simulation outcomes.

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Article Synopsis
  • The study analyzed the biosynthetic capabilities of 11 endophytic strains from coffee and black pepper plants in Vietnam using genome mining and MALDI-TOF mass spectrometry.
  • These strains were classified based on genome comparisons and phylogenetic analysis, identifying one strain, two strains, three strains, and five new genomospecies.
  • The research focused on nonribosomal peptides, revealing tyrocidines as a major product and introducing a new class of pentapeptides called brevipentins, highlighting the strains' biosynthetic potential for classification.
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Seventeen bacterial strains able to suppress plant pathogens have been isolated from healthy Vietnamese crop plants and taxonomically assigned as members of the group. In order to prove their potential as biocontrol agents, we perform a comprehensive analysis that included the whole-genome sequencing of selected strains and the mining for genes and gene clusters involved in the synthesis of endo- and exotoxins and secondary metabolites, such as antimicrobial peptides (AMPs). Kurstakin, thumolycin, and other AMPs were detected and characterized by different mass spectrometric methods, such as MALDI-TOF-MS and LIFT-MALDI-TOF/TOF fragment analysis.

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Cochlear implant (CI) treatment is now established as a successful standard of care for auditory rehabilitation of profoundly deaf or severe hearing loss patients. CI candidates with tinnitus also benefit from improved health-related quality of life (HRQoL) and tinnitus burden. Current CI indications include bilateral (double-sided) profound hearing loss and deafness (DSD), unilateral (single-sided) deafness (SSD), and asymmetric hearing loss (AHL).

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