Publications by authors named "J Vardiman"
Article Synopsis
- This study compared the effects of a single set (SS) versus multiple sets (MS) of resistance exercise on the Akt/PKB signaling pathway, IGF-1, and IGF-1R expression in recreationally active men.
- Sixteen participants underwent three muscle biopsies at different time intervals—before, 15 minutes after, and 180 minutes after exercise—while performing either a single or multiple set leg press.
- Results showed no significant differences between the SS and MS groups in Akt signaling or IGF-1 expression; however, there was a notable increase in IGF-1R expression in the SS group, indicating that a single set may produce similar acute muscle responses to multiple sets.
Introduction: Cutaneous composite lymphoma (CCL) is extremely rare. When 2 potentially distinct lymphoid lesions occur at one skin site, distinguishing between one neoplastic clone and a secondary reactionary lymphoid response versus a second neoplasm is difficult. In this study, we describe a unique case of CCL along with a review of reported cases in literature to identify clues and discuss issues that are relevant to the diagnosis of CCL.
View Article and Find Full Text PDFIn the originally published version of this Article, the GAPDH loading control blot in Fig. 1a was inadvertently replaced with a duplicate of the DNMT2 blot in the same panel during assembly of the figure. This has now been corrected in both the PDF and HTML versions of the Article.
View Article and Find Full Text PDFThe roles of RNA 5-methylcytosine (RNA:mC) and RNA:mC methyltransferases (RCMTs) in lineage-associated chromatin organization and drug response/resistance are unclear. Here we demonstrate that the RCMTs, namely NSUN3 and DNMT2, directly bind hnRNPK, a conserved RNA-binding protein. hnRNPK interacts with the lineage-determining transcription factors (TFs), GATA1 and SPI1/PU.
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