Publications by authors named "J Vanrusselt"
Studying the clinical, radiological, histological, microbiological, and immunological evolution during the different COVID-19 disease stages using minimal invasive autopsy.
Sci Rep
January 2022
Article Synopsis
- The study looked at different stages of COVID-19 and how they affect people's bodies in different ways.
- They examined 44 patients and found that those with mild disease didn't show the typical signs on CT scans while many with severe disease did.
- It was also found that certain harmful changes occurred in the lungs and other organs, stressing the importance of specialized treatment for patients based on their disease stage.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is not always confined to the respiratory system, as it impacts people on a broad clinical spectrum from asymptomatic to severe systemic manifestations resulting in death. Further, accumulation of intra-host single nucleotide variants during prolonged SARS-CoV-2 infection may lead to emergence of variants of concern (VOCs). Still, information on virus infectivity and intra-host evolution across organs is sparse.
View Article and Find Full Text PDFBackground: Minimally invasive autopsy (MIA) is a validated and safe method to establish the cause of death (COD), mainly in low-resource settings. However, the additional clinical value of MIA in Coronavirus disease (COVID-19) patients in a high-resource setting is unknown. The objective was to assess if and how MIA changed clinical COD and contributing diagnoses in deceased COVID-19 patients.
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