Publications by authors named "J Van Zundert"
Article Synopsis
- Long-term conventional spinal cord stimulation (LT-SCS) is effective for treating painful diabetic peripheral neuropathy (PDPN) initially, but its effectiveness may decline over time.
- *In a rat study, LT-SCS led to increased thresholds for mechanical hypersensitivity and changes in nerve fiber density, indicating structural adaptations in response to pain.
- *The study suggests that LT-SCS reduces certain proteins associated with pain pathways, revealing potential mechanisms for its effectiveness in managing PDPN symptoms.*
Intravenous Lidocaine for Refractory Pain in Patients With Pancreatic Ductal Adenocarcinoma and Chronic Pancreatitis: A Multicenter Prospective Nonrandomized Pilot Study.
Clin Transl Gastroenterol
September 2024
Introduction: Refractory pain is a major clinical problem in patients with pancreatic ductal adenocarcinoma (PDAC) and chronic pancreatitis (CP). New, effective therapies to reduce pain are urgently needed. Intravenous lidocaine is used in clinical practice in patients with PDAC and CP, but its efficacy has not been studied prospectively.
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- Cervicogenic headache (CEH) and occipital neuralgia (ON) are types of headaches that originate from the neck and often have overlapping symptoms, making diagnosis challenging and reliant on headache history and physical examinations.
- A literature review from 2015 to August 2022 highlights various conservative and interventional treatments, including pain education, physical therapy, medication, nerve blocks, and advanced techniques like radiofrequency ablation and occipital nerve stimulation for chronic cases.
- Ultimately, radiofrequency treatment is preferred for CEH, while pulsed radiofrequency is recommended for ON, with occipital nerve stimulation as an option for difficult cases.
Introduction: Chronic knee pain is defined as pain that persists or recurs over 3 months. The most common is degenerative osteoarthritis (OA). This review represents a comprehensive description of the pathology, diagnosis, and treatment of OA of the knee.
View Article and Find Full Text PDFIntroduction: Persistent Spinal Pain Syndrome (PSPS) refers to chronic axial pain and/or extremity pain. Two subtypes have been defined: PSPS-type 1 is chronic pain without previous spinal surgery and PSPS-type 2 is chronic pain, persisting after spine surgery, and is formerly known as Failed Back Surgery Syndrome (FBSS) or post-laminectomy syndrome. The etiology of PSPS-type 2 can be gleaned using elements from the patient history, physical examination, and additional medical imaging.
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