Publications by authors named "J Van Humbeeck"

Besides the unique shape memory effect and superelasticity, NiTi alloys also show excellent damping properties. However, the high damping effect is highly temperature-dependent, and only exists during cooling or heating over the temperature range where martensitic transformation occurs. As a result, expanding the temperature range of martensite transformation is an effective approach to widen the working temperature window with high damping performance.

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The addition of 0.1 wt % carbon nanoparticles significantly improved the optical absorption and flowability of gas-atomized copper powder. This facilitated selective laser melting (SLM) by reducing the required laser energy density to obtain 98% dense parts.

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Due to unique functional and mechanical properties, NiTi shape memory alloys are one of the most promising metallic functional materials. However, the poor workability limits the extensive utilization of NiTi alloys as components of complex shapes. The emerging additive manufacturing techniques provide high degrees of freedom to fabricate complex structures.

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The microstructure of pharmaceutical semicrystalline solid dispersions has attracted extensive attention due to its complexity that might result in the diversity in physical stability, dissolution behavior, and pharmaceutical performance of the systems. Numerous factors have been reported that dictate the microstructure of semicrystalline dispersions. Nevertheless, the importance of the complicated conformation of the polymer has never been elucidated.

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The crystallization of metastable crystal polymorphs in polymer matrices has been extensively reported in literature as a possible approach to enhance the solubility of poorly water-soluble drug compounds, yet no clarification of the mechanism of the polymorph formation has been proposed. The current work aims to elucidate the polymorphism behavior of the model compound indomethacin as well as the mechanism of polymorph selection of drugs in semicrystalline systems. Indomethacin crystallized as either the α- or τ-form, a new metastable form, or a mixture of the two polymorphs in dispersions containing different drug loadings in polyethylene glycol, poloxamer, or Gelucire as the result of the variation in the mobility of drug molecules.

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