Publications by authors named "J Vallverdu"
Background: In this study we investigate the selective compensation of paired peripheral nerves in healthy humans, focusing on distinct axonal conduction velocities in different fibre types. Using paired associative stimulation (PAS) with adjustable parameters, we aimed to modulate and compensate for neuronal activity along the median nerve.
Methods: Six healthy volunteers (3 male, 3 female, aged: 22-49) participated in the current study.
Background: Driving pressure is thought to determine the effect of low tidal ventilation on survival in patients with acute respiratory distress syndrome. The leading cause of mortality in these patients is non-pulmonary multiorgan dysfunction, which is believed to worsen due to the biological response to mechanical ventilation (biotrauma). Therefore, we aimed to analyze the association between driving pressure, biotrauma, and non-pulmonary multiorgan dysfunction.
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- Increasing evidence of Neanderthal osseous industry shows they used bone fragments for practical tools, with diverse shaping techniques, but no bone spear points were previously identified in these contexts.
- A detailed study of a bone spear point from the Abric Romaní site in Spain reveals its manufacture and use, with clear signs of intentional knapping and wear patterns consistent with serving as a spear.
- This finding enhances our understanding of Neanderthal hunting behavior and highlights the adaptability of their technology 50,000 years ago, shedding light on previously overlooked aspects of their tool-making strategies.
Background: Postoperative pulmonary complications (PPC) are the most frequent postoperative complications, with an estimated prevalence in elective surgery ranging from 20% in observational cohort studies to 40% in randomized clinical trials. However, the prevalence of PPCs in patients undergoing emergency abdominal surgery is not well defined. Lung-protective ventilation aims to minimize ventilator-induced lung injury and reduce PPCs.
View Article and Find Full Text PDFBackground: It is uncertain whether individualisation of the perioperative open-lung approach (OLA) to ventilation reduces postoperative pulmonary complications in patients undergoing lung resection. We compared a perioperative individualised OLA (iOLA) ventilation strategy with standard lung-protective ventilation in patients undergoing thoracic surgery with one-lung ventilation.
Methods: This multicentre, randomised controlled trial enrolled patients scheduled for open or video-assisted thoracic surgery using one-lung ventilation in 25 participating hospitals in Spain, Italy, Turkey, Egypt, and Ecuador.