Publications by authors named "J Valeur"

Article Synopsis
  • - The study aimed to understand how different diets (higher-carbohydrate vs. low-carbohydrate) affect gastrointestinal health, symptoms, quality of life, and fecal short-chain fatty acids (SCFAs) in individuals with obesity over 12 months.
  • - Participants were divided into three dietary groups: one with refined carbs, one with minimally refined carbs, and a low-carb high-fat diet, with no significant weight loss differences observed in the long term.
  • - While fiber intake increased in all groups, there were no notable changes in irritable bowel syndrome symptoms, but significant improvements in reflux symptoms were reported in one dietary group after 12 months.
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Article Synopsis
  • The study examined the relationship between low disaccharidase enzyme activity and gastrointestinal symptoms, particularly in patients with irritable bowel syndrome (IBS).
  • Out of 40 patients, 60% had disaccharidase deficiency, and half of those met the criteria for IBS, but most reported severe gastrointestinal symptoms regardless of enzyme levels.
  • The results indicated no significant correlation between the level of disaccharidase deficiency and the severity of symptoms or the diagnosis of IBS.
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Article Synopsis
  • * Results show that different diets influenced specific gut bacterial taxa, with FOS increasing Fusicatenibacter and gluten increasing Eubacterium xylanophilum, but no significant changes in overall bacterial diversity or gut metabolites were observed.
  • * Gastrointestinal symptoms after FOS consumption were not directly linked to notable shifts in the gut bacteria, although a reduction in Eubacterium (E. coprostanoligenes) was associated with increased gastrointestinal pain.
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Background: Reduced activity of the sucrase-isomaltase (SI) enzyme can cause gastrointestinal symptoms. Biochemical measurement of SI activity in small intestinal biopsies is presently considered the gold standard for the diagnosis of SI deficiency, but this invasive test is not suitable as a routine diagnostic tool.

Aim: To evaluate a C-sucrose-breath test (CSBT) as a diagnostic tool for SI deficiency in an adult population.

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Background: The relationship between gut microbiota and irritable bowel syndrome (IBS) subtype is unclear. We aimed to explore whether differences in fecal bacteria composition and short-chain fatty acid (SCFA) levels were associated with subtypes and symptoms of IBS.

Methods: All participants delivered fecal samples and self-reports on IBS Symptom Severity Score (IBS-SSS), Bristol Stool Scale (BSS), and Gastrointestinal Symptom Rating Scale (GSRS).

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