Background: Peripheral T-cell lymphomas represent a rare and heterogeneous group of mature T-cell neoplasms characterised by aggressive behavior. Previous studies evaluating peripheral T-cell lymphoma epidemiology across Latin America have been restricted in their representation of most countries in the region. In this study, we aimed to describe peripheral T-cell lymphoma epidemiology across Latin America.
View Article and Find Full Text PDFA proper, reliable, and economic operation of a power system relies on a precise energy management strategy. For a reliable energy management strategy, information about the power system including power production and power consumption is required. However, consumer behaviour can be unpredictable, which can result to a high level of uncertainties for the load profile.
View Article and Find Full Text PDFContext: The baseball athlete incorporates the use of the entire kinetic chain while throwing. Hip range of motion (ROM) and strength have been previously studied in its relation to injury development. It is a clinical necessity to understand the normative profiles of hip musculoskeletal function across the playing career.
View Article and Find Full Text PDFGlioblastoma (GBM) carries a dismal prognosis, with a median survival of less than 15 months. Temozolomide (TMZ), the standard frontline chemotherapeutic for GBM, is an alkylating agent that generates DNA O-methylguanine (OMeG) lesions. Without OMeG-methyltransferase (MGMT), this lesion triggers the mismatch repair (MMR) pathway and leads to cytotoxicity via futile cycling.
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