Comparison of Real and Simulated Fiber Orientations in Injection Molded Short Glass Fiber Reinforced Polyamide by X-ray Microtomography.

During injection molding of short glass fiber reinforced composites, a complex structure is formed due to the fiber movement. The resulting fiber orientation can be predicted using various simulation models. However, the models are known to have inadequacies andthe influence of process and model parameters is not clearly and comprehensively described.

Narrative review of metabolomics in cardiovascular disease.

Cardiovascular diseases are accompanied by disorders in the cardiac metabolism. Furthermore, comorbidities often associated with cardiovascular disease can alter systemic and myocardial metabolism contributing to worsening of cardiac performance and health status. Biomarkers such as natriuretic peptides or troponins already support diagnosis, prognosis and treatment of patients with cardiovascular diseases and are represented in international guidelines.

CCR2-dependent Gr1 monocytes promote kidney injury in shiga toxin-induced hemolytic uremic syndrome in mice.

The hemolytic uremic syndrome (HUS) is a life-threatening disease of the kidney that is induced by shiga toxin-producing E.coli. Major changes in the monocytic compartment and in CCR2-binding chemokines have been observed.

-dependent CD103CD11b dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus.

Objective: Postoperative ileus (POI), the most frequent complication after intestinal surgery, depends on dendritic cells (DCs) and macrophages. Here, we have investigated the mechanism that activates these cells and the contribution of the intestinal microbiota for POI induction.

Design: POI was induced by manipulating the intestine of mice, which selectively lack DCs, monocytes or macrophages.

Neutrophil Migration into the Infected Uroepithelium Is Regulated by the Crosstalk between Resident and Helper Macrophages.

The antibacterial defense against infections depends on the cooperation between distinct phagocytes of the innate immune system, namely macrophages and neutrophils. However, the mechanisms driving this cooperation are incompletely understood. In this study we describe the crosstalk between Ly6C⁺ and Ly6C(-) macrophage-subtypes and neutrophils in the context of urinary tract infection (UTI) with uropathogenic E.