Publications by authors named "J V Simmonds"

In 2024, there have been increases in laboratory confirmed infections of Mycoplasma Pneumoniae infection worldwide. This case series highlights increasing frequency of Mycoplasma pneumoniae positive PCR specimens and an increased number of hospital admissions with Mycoplasma pneumoniae clinical syndromes. Within this case series, we observed, a change in the epidemiology and clinical burden of childhood Mycoplasma pneumonia disease in the post COVID-19 era.

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Article Synopsis
  • The study investigates the use of mechanical circulatory support (MCS) in pediatric heart transplant patients, focusing on incidence, contributing factors, and outcomes based on a large database from 2010-2020.
  • Among 4,321 primary heart transplants analyzed, 5.8% (249 patients) required MCS, with factors like congenital heart disease and older donor age linked to higher MCS need, while larger recipient size and better donor heart function correlated with lower needs.
  • The one-year survival rate for patients requiring MCS was significantly lower at 54.2% compared to 94.8% for those without, but those who survived the first year had favorable long-term outcomes, suggesting selective use of MCS
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Advances in medicine allow children with previously fatal conditions to survive longer and present as transplant candidates; some requiring multiple solid-organ transplants (MSOT). There is limited data on clinical outcomes and no data on quality of life (QoL). In this mixed methods cohort study clinical outcomes from the NHSBT registry were analysed for all patients who received a kidney and one other solid-organ transplant as a child between 2000 and 2021 in the UK.

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Many nations are struggling to reduce deforestation, despite having extensive environmental protection laws in place and commitments to international agreements that address the biodiversity and climate crises. We developed a novel framework to quantify the extent to which contemporary deforestation is being captured under national and subnational laws. We then applied this framework to northern Australia as a case study, a development and deforestation hotspot with ecosystems of global significance.

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