Publications by authors named "J V Khang"
Introduction: Subthalamic nucleus deep brain stimulation (STN DBS) improves motor symptoms of Parkinson's disease (PD), but its effect on motivation is controversial. Apathy, the lack of motivation, commonly occurs in PD and is often exacerbated after surgery and its concomitant levodopa reduction. Apathy and reward processing are associated with the ventromedial prefrontal cortex (vmPFC), which standard targeting strategies avoid by targeting the dorsolateral STN.
View Article and Find Full Text PDFArticle Synopsis
- COVID-19 has caused higher death rates in men than women despite similar infection rates, prompting research into the biological reasons behind this disparity.
- Researchers found that female mice had a unique protein expression profile in their lungs, leading to better protection against severe infections due to increased ACE2 expression and a favorable balance of estrogen and androgen receptors.
- The study suggests that inhaling recombinant ACE2 may help protect male mice from severe infections by acting as a decoy for the virus and also shows promise for treating human lung organoids infected with the Delta variant.
Face recognition is impaired in autism spectrum disorders (ASDs), but the reason for this remains unclear. One possibility is that impairments in the ability to visually detect faces might be a factor. As a preliminary study in this vein, we measured face detection ability as a function of visual contrast level in 13 individuals with ASD, aged 13-18, and 18 neurotypical controls (NCs) in the same age range.
View Article and Find Full Text PDF