Publications by authors named "J V Guarrera"
The lack of health insurance is a major barrier to access to health care, even in the case of life-saving procedures such as liver transplantation (LT). Concerns about worse outcomes in uninsured patients have also discouraged the evaluation and transplantation of patients without adequate health insurance coverage. The aim of this study is to evaluate outcomes from the largest cohort of uninsured patients who underwent LT with the support of a state payment assistance program (also called charity care).
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- Scientists are studying how to tell if a donated liver is healthy enough to use for transplant by looking at special markers during a process called HOPE.
- They collected samples from livers in 10 different centers across 7 countries and found that the levels of a marker called FMN can help predict if the liver will work well after being transplanted.
- The study showed that FMN is better at predicting liver problems compared to older methods, making it a promising tool for doctors to decide which livers are suitable for transplant.
Background: The American Society of Transplant Surgeons convened a multidisciplinary working group to address operational, ethical, and legal considerations surrounding normothermic regional perfusion (NRP) procurement.
Methods: The working group, comprising members from American Society of Transplant Surgeons and AST across various disciplines including transplant surgery, hepatology, critical care, and bioethics, collaborated to formulate recommendations and guidance for NRP procurement.
Results: The following topics were identified by the group as essential standards that need to be addressed for ethical, legal, and operational conformance: terminology; conceptualization of death in the context of NRP; and communication, logistics, and training and competency.
Sebaceomas in a Muir-Torre-like Phenotype in a Patient with MUTYH-Associated Polyposis.
Dermatopathology (Basel)
March 2024
Article Synopsis
- - The case report discusses a patient with MUTYH-associated polyposis (MAP), presenting symptoms similar to Muir-Torre syndrome, including multiple sebaceomas.
- - MAP results from mutations in the MUTYH gene, which is involved in DNA repair and is linked to a higher risk of colorectal cancer and adenomatous polyps.
- - The findings suggest that patients showing multiple sebaceous neoplasms should undergo additional genetic testing to rule out MAP, as well as Muir-Torre and Lynch syndrome.