Publications by authors named "J V Amerena"

Introduction And Objectives: Clozapine is the antipsychotic medication with the greatest efficacy in treatment-resistant schizophrenia (TRS). Unfortunately, clozapine is ceased in approximately 0.2% to 8.

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Article Synopsis
  • The study investigates how age affects left ventricular (LV) recovery and atrial fibrillation (AF) recurrence in patients with AF and systolic heart failure who do not have ventricular scar tissue after catheter ablation.
  • Researchers divided 70 patients into younger (<65 years) and older (≥65 years) groups, assessing various heart metrics and treatment strategies, finding no significant differences in LV function or AF outcomes.
  • The findings suggest that both age groups experienced similar levels of freedom from AF and LV recovery post-ablation, indicating that age may not significantly impact these outcomes in patients without myocardial fibrosis.
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Background: Cardiac distress may be viewed as a persistent negative emotional state that spans multiple psychosocial domains and challenges a patient's capacity to cope with living with their heart condition. The Cardiac Distress Inventory (CDI) is a disease-specific clinical assessment tool that captures the complexity of this distress. In busy settings such as primary care, cardiac rehabilitation, and counselling services, however, there is a need to administer briefer tools to aid in identification and screening.

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Background: Many challenges are posed by the experience of a heart attack or heart surgery which can be characterised as 'cardiac distress'. It spans multiple psychosocial domains incorporating patients' responses to physical, affective, cognitive, behavioural and social symptoms and experiences related to their cardiac event and their recovery. Although some measures of the psychological and emotional impacts of a cardiac event exist, none provides a comprehensive assessment of cardiac distress.

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Background: Lower urinary sodium concentrations (U) may be a biomarker for poor prognosis in chronic heart failure (HF). However, no data exist to determine its prognostic association over the long-term. We investigated whether U predicted major adverse coronary events (MACE) and all-cause mortality over 28-33 years.

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