Publications by authors named "J Tyrrell"

Article Synopsis
  • Medications that can cause sedation or have anticholinergic effects pose risks for those with cognitive issues, especially in individuals with intellectual disabilities (ID), who may experience increased frailty and adverse effects.
  • A study assessed the drug burden in a group of patients with ID who were referred for cognitive evaluation, finding that a majority were on multiple medications, with significant use of sedatives and anticholinergics.
  • Results indicated that individuals with psychiatric comorbidities and certain types of ID had higher drug burden index scores, suggesting a need for careful medication management in this population.
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Disordered eating and self-harm commonly co-occur in young people suggesting potential for shared underlying causes. Body image dissatisfaction (BID) has been recognised as a psychological correlate of body size, associated with both disordered eating and self-harm. However, the investigation into etiological pathways early in the lifecourse to provide detail on how body size and BID may foster disordered eating and self-harm remains largely unexplored.

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Colorectal cancer (CRC) is a leading cause of cancer mortality worldwide. Accurate cancer risk assessment approaches could increase rates of early CRC diagnosis, improve health outcomes for patients and reduce pressure on diagnostic services. The faecal immunochemical test (FIT) for blood in stool is widely used in primary care to identify symptomatic patients with likely CRC.

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Since 2018, the 'Superbugs' initiative at Cardiff University (United Kingdom) has been delivering projects that take a research-driven approach to public engagement, involving rigorous evaluation of the methodologies of delivery and the mechanics of communication. The overall aim of Superbugs is to raise awareness and improve public knowledge of microbiology, infection and antimicrobial resistance (AMR). In the present project, four postgraduate students were recruited to undertake research projects as part of their Master of Science (MSc) studies.

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