Temperature-Dependent Kinetics of the Reactions of the Criegee Intermediate CHOO with Aliphatic Aldehydes.

Criegee intermediates, formed by alkene ozonolysis in the troposphere, can react with volatile organic compounds (VOCs). The temperature-dependent kinetics of the reactions between the Criegee intermediate CHOO and three aliphatic aldehydes, RCHO where R = H, CH, and CH (formaldehyde, acetaldehyde, and propionaldehyde, respectively), have been studied using a laser flash-photolysis transient absorption spectroscopy technique. The experimental measurements are supported by calculations at various composite levels of theory that characterize stationary points on the reaction potential and free energy surfaces.

Auranofin is lethal against feline Tritrichomonas foetus in vitro but ineffective in cats with naturally occurring infection.

Protozoal diarrhea caused by Tritrichomonas foetus (blagburni) is a prevalent, lifelong, and globally distributed burden in domestic cats. Treatment is limited to the use of 5-nitroimidazoles and treatment failure is common. The repurposed gold salt compound auranofin has killing activity against diverse protozoa in vitro but evidence of efficacy in naturally occurring protozoal infections is lacking.

Non-Targeted PFAS Suspect Screening and Quantification of Drinking Water Samples Collected through Community Engaged Research in North Carolina's Cape Fear River Basin.

A community engaged research (CER) approach was used to provide an exposure assessment of poly- and perfluorinated (PFAS) compounds in North Carolina residential drinking water. Working in concert with community partners, who acted as liaisons to local residents, samples were collected by North Carolina residents from three different locations along the Cape Fear River basin: upper, middle, and lower areas of the river. Residents collected either drinking water samples from their homes or recreational water samples from near their residence that were then submitted by the community partners for PFAS analysis.

Predicting cognitive function and dementia risk in patients with hypertension.

In spite of the fact that hypertension stand out as the main vascular risk factor for developing dementia, it is essential to acknowledge the presence of other risk factors, both vascular and non-vascular that contribute to increase this risk. This study stratified the dementia risk using CAIDE (Cardiovascular Risk Factors, Aging, and Incidence of Dementia) dementia risk score in a sample of 1279 hypertensive patients from the Heart-Brain Study in Argentina and to observed the association between the risk factors include in the CAIDE score and the current cognitive status. The average age of the sample was 60.